KLARICID IV PDF
Klaricid IV mg (PL /, Abbott Laboratories Ltd). No new or unexpected safety concerns arose from this application and it was therefore judged that. Indications, side effects, contraindications and other prescribing information for Klaricid IV on MIMS. Clarithromycin is indicated in: Lower respiratory tract infection: acute and chronic bronchitis and pneumonia;; Upper respiratory tract infection: sinusitis and.
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Klaricid IV Injection Clarithromycin. View All Brand Names of this Generic. Clarithromycin is indicated in: Lower respiratory tract infection: Clarithromycin acts by inhibiting microsomal protein synthesis in susceptible organisms mainly by binding to the donor site on the 50S sub- unit of the bacterial ribosome and preventing translocation to that site. Clarithromycin is active against most Gram-positive bacteria and Chlamydia, some Gram-negative bacteria and Mycoplasmas.
Clarithromycin is more acid stable than erythromycin and therefore, is better tolerated. Clarithromycin has twice the activity of erythromycin against H. Most species of Gram-negative bacteria are resistant to clarithromycin because of failure to penetrate to the target.
Body weight under 8 kg: Clarithromycin mg twice daily and lansoprazole 30mg twice daily should be given with amoxycillin mg twice daily. Clarithromycin mg twice daily and lansoprazole 30mg twice daily should be given with metronidazole mg twice daily. Clarithromycin mg twice daily and omeprazole 40mg daily should be given i amoxycillin mg twice daily or metronidazole mg twice daily.
Clarithromycin mg twice daily should be given with amoxycillin mg twice daily and omeprazole 20mg daily.
Klaricid-I.V mg Inf – Clarithromycin – Price in Pakistan –
The usual dose of Clarithromycin is mg three times daily for 14 days. Clarithromycin should be administered with oral omeprazole kllaricid once daily. The pivotal study was conducted with omeprazole 40mg once daily for 28 days. Supportive studies have been conducted with omeprazole 40mg once daily for 14 days.
Kv use of clarithromycin who are receiving theophylline may be associated with an increase in serum theophylline concentrations. Clarithromycin may alter the metabolism of terfenadine.
Clarithromycin may increase area under the serum concentration-time curve AUC for carbamazepine and decreased peak serum concentration and AUC for carbamazepine. Hypersensitive to Clarithromycin, Erythromycin or any of the macrolide antibiotics.
Patients receiving terfenadine who have pre-existing cardiac abnormalities or electrolyte disturbances. The most frequent and common adverse reactions related to clarithromycin therapy for both adult and peadiatric populations are abdominal pain, diarrhoea, nausea, vomiting and taste perversion. These adverse reactions are usually mild in intensity and are consistent with the known safety profile of macrolide antibiotics.
There was no significant difference in the incidence of these gastrointestinal adverse reactions during clinical trials between the patient population with or without pre-existing mycobacterial infections. Clarithromycin is not recommended for pregnant women. Breast milk from mothers receiving Clarithromycin should not be given to infants until treatment is completed. Caution should be taken in administering this antibiotic to patients with impaired hepatic and klaricd function.
KLARICID IV 500 MG
klaricld Prolonged or repeated use of Clarithromycin may result in an overgrowth of nonsusceptible bacteria or fungi. If superinfection occurs, Clarithromycin should be discontinued. Pharmaceutical precaution Clarithromycin tablet should be stored in a cool and dry place and away from sunlight.
Ingestion of large amounts of Clarithromycin can be expected to produce gastrointestinal symptoms. Symptoms of overdose may largely correspond to the profile of side effects.
There is no specific antidote on overdose. Serum levels of Clarithromycin can not be reduced by haemodialysis or peritoneal dialysis.
CLARITHROMYCIN | Drug | BNF content published by NICE
Clarithromycin may be used in neonates and children in appropriate doses. The usual duration of treatment is 6 to 14 days. Children older than 12 years: The concentration of clarithromycin in the reconstituted suspension is mg per 5 ml.